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The relationship between changes in alcohol consumption and hepatic steatosis among alcohol consumers: a large-scale population-based Biobank study

Abstract: The relationship between changes in alcohol consumption and hepatic steatosis among alcohol consumers remains poorly understood. This study aimed to evaluate the…

Date: 2025-10-16

Exploring the carcinogenic potential of bisphenol A in lung adenocarcinoma: molecular mechanisms, key gene insights, and immune microenvironment impacts

Abstract: Bisphenol A (BPA) is an endocrine-disrupting chemical that may contribute to cancer development. However, its role in lung adenocarcinoma (LUAD) remains poorly…

Date: 2025-10-16

Mass cytometric analysis of circulating immune landscape in primary central nervous system lymphoma

Abstract: The peripheral immune profiles of patients with primary central nervous system lymphoma (PCNSL) remain poorly characterized. Investigating immune dysregulation in PCNSL…

Date: 2025-10-15

Bach2 -deficient mice are prone to autoimmune pancreatitis but protected from high-fat diet-induced fatty liver disease

Abstract: Autoimmune pancreatitis (AIP) is a multifactorial disease caused by both genetic and environmental factors. Previous studies have implicated Bach2, a key regulator of…

Date: 2025-10-15

Coping tendencies play partial mediating role between social support and anxiety/depression among Chinese keloid patients

Abstract: In addition to producing pain and itching, keloids can cause psychological symptoms, including anxiety and depression. We aimed to investigate the prevalence and…

Date: 2025-10-15

Ipsa senectus morbus est? Approaching the unmet needs in geriatric depression: results from a national survey of medical experts

Abstract: One of the main challenges of “real-world” management of depression is represented by geriatric depression, which is common and under-diagnosed. Depressive disorders…

Date: 2025-10-15

A comparative study of online and face-to-face gatekeeper training using the suicide CARE program

Abstract: Gatekeeper training programs are essential public health strategies for suicide prevention. With the rapid digitization of health education, evaluating the effectiveness…

Date: 2025-10-15

Post-discharge use of opioids, psychostimulants, and treatment medications following residential opioid discontinuation with NET Device™ monotherapy

Abstract: Medical devices offer an established therapeutic approach for managing the transition from polysubstance use to abstinence, but little is known about longer-term…

Date: 2025-10-15

The economic burden of anxiety and depression in Indonesia: evidence from a cross-sectional web panel survey

Abstract: Mental health conditions are the second leading cause of disability in Indonesia, accounting for 13 percent of total years lived with disability. However, little is…

Date: 2025-10-15

Ultrasonographic assessment of optic nerve sheath diameter on the affected and unaffected sides as a predictor of clinical deterioration at discharge in patients with large hemispheric infarction

Abstract: Progressive cerebral edema worsens prognosis in large hemispheric infarction (LHI). Ultrasonographic optic nerve sheath diameter (ONSD) measurement provides a…

Date: 2025-10-15