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Research Articles Search

Showing 850 of 147,163 result(s)
Tau protein mediates the association between frailty and postoperative delirium: a machine learning model incorporating cerebrospinal fluid biomarkers

Abstract: Postoperative delirium (POD) is a prevalent neurological complication linked to adverse clinical outcomes. The underlying mechanisms of POD remain unclear. This study…

Date: 2025-10-01

Association between vitamin D deficiency and risk of venous thromboembolism: a matched cohort study of 139,690 patients

Abstract: Vitamin D deficiency (VDD) may contribute to venous thromboembolism (VTE) through effects on coagulation and endothelial function, but existing studies show inconsistent…

Date: 2025-10-01

Effectiveness and safety of ciprofol for the induction and maintenance of general anesthesia in urological surgery: a prospective, non-inferiority cohort study

Abstract: Ciprofol is a newly developed intravenous agent, with limited clinical data available to date. The study aimed to evaluate the effectiveness and safety of ciprofol for…

Date: 2025-10-01

Retrospective efficacy analysis of stellate ganglion block combined with general anesthesia in arthroscopic shoulder surgery: a cohort study

Abstract: Although arthroscopic shoulder surgery confers clear advantages for recovery, it is often complicated by intraoperative hemodynamic instability and prolonged…

Date: 2025-10-01

Lipocalin-2 in preoperative cerebrospinal fluid is a biomarker for postoperative delirium after hip fracture surgery in older adults: a prospective cohort study

Abstract: Postoperative delirium (POD) is a common central nervous system complication in older adult surgical patients. At present, the mechanism for POD is still unclear.…

Date: 2025-10-01

Global burden of disease among adolescents and young adults with drug use disorders, 1990–2021: based on GBD 2021

Abstract: The objective of this study was to assess the distribution and trends in the prevalence of drug use disorders (DUDs) among adolescents and young adults (aged 15 to 39…

Date: 2025-10-01

Safety and efficacy evaluation of low-dose of esketamine combined with propofol for painless gastroscopy: a single-center, randomized, double-blind, parallel controlled clinical trial

Abstract: Propofol combined with sufentanil is the most commonly used anesthesia regimen for painless gastroscopy in China. However, this combination carries a higher risk of…

Date: 2025-10-01

Learning curve of ultrasound-guided caudal epidural block: a CUSUM pivotal analysis

Abstract: This study aims to dynamically evaluate the learning curve of anesthesiology residents’ mastery of ultrasound-guided caudal epidural block (US-CEB) through cumulative…

Date: 2025-10-01

Systemic immune inflammatory index and mortality in chronic kidney disease

Abstract: Chronic kidney disease (CKD) is common and linked to higher mortality rates, but its relationship with the systemic immunoinflammatory index (SII) remains unclear,…

Date: 2025-10-01

Evaluating the toxicity profile of combination immune checkpoint inhibitors: a disproportionality analysis of real-world adverse events from the FDA Adverse Event Reporting System for tremelimumab, durvalumab, ipilimumab, and nivolumab

Abstract: As one of the therapeutic modalities for treating tumors, immune checkpoint inhibitors (ICIs) have gained widespread application in clinical practice, including…

Date: 2025-10-01