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Clinical trial landscape and translational priorities for adoptive T-cell and NK-cell therapies in gynecologic malignancies

Abstract: Adoptive T-cell and natural killer (NK)-cell therapies are expanding across solid tumors, but their registered development in gynecologic malignancies remains difficult…

Date: 2026-09-28

Standardizing a human TBMNK cell assay across instrument platforms: a new framework for producing high-quality, AI-ready reference dataset

Abstract: Recent advances in regenerative medicine advanced therapies (RMAT) are revolutionizing health care by providing curative treatments for previously untreatable diseases.…

Date: 2026-09-28

Analysis of the subject-object effects and chain mediation of psychosocial factors in couples during late pregnancy on depression: a cross-sectional study of pregnant women and their spouses

Abstract: To examine, from a dual-perspective approach, the actor and partner associations of couples' perceptions of stress, rumination, self-efficacy, self-disclosure, and…

Date: 2026-09-28

Barriers and facilitators to telerehabilitation adherence in young and middle-aged stroke survivors: a qualitative COM-B analysis

Abstract: To explore the barriers and facilitators to telerehabilitation adherence among young and middle-aged stroke survivors using the Capability, Opportunity,…

Date: 2026-09-28

Identification and validation of feature genes using a ferroptosis-informed analytical framework in medulloblastoma

Abstract: This study aimed to identify potential biomarker signatures for medulloblastoma using a ferroptosis-informed analytical framework. Transcriptomic data from GEO datasets…

Date: 2026-09-28

Ginsenoside Rb2 promotes p62-mediated LDHA autophagic degradation to inhibit H3K18la-dependent PD-L1 transcription in cervical cancer

Abstract: Ginsenoside Rb2 has demonstrated antitumor activity in multiple malignancies, yet its role in cervical cancer and the underlying mechanism remain unclear. This study…

Date: 2026-09-28

Real-world anatomical and functional outcomes following Faricimab therapy in neovascular age-related macular degeneration: a one-year observational study

Abstract: This study evaluated 12-month anatomical and functional outcomes of Faricimab in Italian patients with neovascular age-related macular degeneration (nAMD). 30 eyes from…

Date: 2026-09-28

Albuminuria, kidney function, and automatically quantified retinal vascular phenotypes in hospitalized adults with type 2 diabetes

Abstract: To compare albuminuria and creatinine-based estimated glomerular filtration rate (eGFR) in relation to automatically quantified retinal vascular phenotypes from color…

Date: 2026-09-28

Association between the stress hyperglycemia ratio and neovascular glaucoma in patients with proliferative diabetic retinopathy

Abstract: Neovascular glaucoma (NVG) is a sight-threatening complication of proliferative diabetic retinopathy (PDR). The stress hyperglycemia ratio (SHR), which quantifies the…

Date: 2026-09-28