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The pan-immune-inflammation value predicts stroke-associated pneumonia and poor outcome in spontaneous intracerebral hemorrhage: a machine learning approach

Abstract: Stroke-associated pneumonia (SAP) constitutes a major complication following spontaneous intracerebral hemorrhage (sICH), posing a significant clinical challenge for…

Date: 2026-09-17

Correlation analysis of serum brain-derived neurotrophic factor, matrix metalloproteinase-9, and glutamate levels changes after repetitive transcranial magnetic stimulation intervention with functional improvement in patients with acute ischemic stroke

Abstract: To explore the correlation of serum brain-derived neurotrophic factor (BDNF), matrix metalloproteinase-9 (MMP-9), and glutamate (Glu) changes with functional recovery…

Date: 2026-09-17

MGST3 defines a mitochondrial-health-associated M2 macrophage state in atherosclerosis: integrative multi-omics, single-cell mediation, and functional validation

Abstract: Mitochondrial dysfunction is increasingly recognized as a driver of maladaptive macrophage polarization in atherosclerosis (AS), but the mitochondrial genes that shape…

Date: 2026-09-17

Vibroacoustic lung therapy and early postoperative oxygenation after cardiac surgery: a multicentre prospective study

Abstract: Postoperative respiratory dysfunction remains a clinically significant problem after cardiac surgery. However, clinical evidence on vibroacoustic pulmonary therapy in…

Date: 2026-09-17

Early endocrine diagnoses and subsequent survival after immune checkpoint inhibitor initiation in non-small cell lung cancer: a 180-day landmark cohort study

Abstract: Endocrine diagnoses newly recorded after immune checkpoint inhibitor (ICI) initiation may be associated with subsequent outcomes, but time-dependent bias and the…

Date: 2026-09-17

Cumulative pre-chemoimmunotherapy dexamethasone dose is associated with adverse outcomes in primary central nervous system lymphoma

Abstract: Dexamethasone is administered postoperatively and concomitantly with induction regimens and consolidation therapy in patients with primary central nervous system…

Date: 2026-09-17

A stepwise institutional approach to refractory autoimmune cytopenia after allogeneic stem cell transplantation in children: a retrospective case series

Abstract: Refractory autoimmune cytopenia (AIC) after allogeneic hematopoietic stem cell transplantation carries substantial morbidity and mortality in children. Conventional…

Date: 2026-09-17

Real-world treatment outcomes in pregnancy and lactation-associated osteoporosis: a nationwide multicenter cohort study

Abstract: Pregnancy and lactation-associated osteoporosis (PLO) is an uncommon cause of fragility fractures in young women, and the optimal treatment strategy remains unclear.…

Date: 2026-09-17

Age- and sex-specific associations of underweight and excess adiposity with incident CKD in type 2 diabetes: nationwide Korean cohort study

Abstract: Obesity is a well-established risk factor for diabetic chronic kidney disease (CKD), but the relationship between body mass index (BMI) and CKD risk remains…

Date: 2026-09-17

Natural history of hypophosphatasia in Chinese patients younger than 18 years: a single-center retrospective observational study

Abstract: To summarize the clinical features, natural history, and ALPL variant spectrum of Chinese children with hypophosphatasia (HPP), and to evaluate diagnostic features…

Date: 2026-09-17