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A prospective, multi-center, phase IV clinical study to assess the safety and clinical outcome of acalabrutinib in Indian adult patients with chronic lymphocytic leukemia/small lymphocytic lymphoma or relapsed/refractory mantle cell lymphoma

Abstract: To evaluate the safety and clinical outcomes of acalabrutinib in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) or refractory/relapsed…

Date: 2026-09-10

Multiscale characterization of an inflammatory macrophage state associated with an air pollutant–prioritized prognostic signature in gastric cancer

Abstract: Air pollutants are implicated in carcinogenesis, but their relevance to gastric cancer (GC) across prognosis, tumor organization and cell behavior remains unclear. We…

Date: 2026-09-10

Incremental prognostic value of pan-immune-inflammation value in conservatively treated acute myocardial infarction: derivation and MIMIC-IV validation

Abstract: Immune-inflammatory activation contributes to adverse outcomes after acute myocardial infarction (AMI). the study evaluated whether the pan-immune-inflammation value…

Date: 2026-09-10

Hemoglobin glycation index and prognosis after successful chronic total occlusion percutaneous coronary intervention: a retrospective cohort study

Abstract: Even after technically successful percutaneous coronary intervention (PCI) for chronic total occlusion (CTO), patients face persistent excess cardiovascular risk. The…

Date: 2026-09-10

Prognostic value of hemoglobin-to-serum creatinine ratio in patients with coronary artery disease and reduced kidney function following percutaneous coronary intervention

Abstract: This investigation sought to assess the prognostic significance of the hemoglobin-to-serum creatinine (Hb/SCr) ratio for long-term survival among patients with…

Date: 2026-09-10

Multiparametric CMR evaluation of myocardial remodeling in dystrophinopathy

Abstract: Cardiac involvement in dystrophinopathy progresses from diffuse myocardial remodeling to overt systolic failure. Multiparametric cardiac magnetic resonance (CMR) offers…

Date: 2026-09-10

Mortality prediction in the elderly patients with coronary artery disease and atrial fibrillation: a retrospective machine learning approach

Abstract: Elderly patients with coexisting coronary artery disease (CAD) and atrial fibrillation (AF) are at significantly increased risk of mortality. Accurate risk…

Date: 2026-09-10

Clinical characteristics of gut microbiota translocation after acute myocardial infarction and its impact on prognosis

Abstract: To systematically analyze the clinical characteristics of gut microbiota translocation in patients after acute myocardial infarction (AMI), explore the relationships…

Date: 2026-09-10

Clinico-microbiological investigation of factors contributing to suboptimal viral suppression among HIV/AIDS patients on sustained antiretroviral treatment in the upper east region of Ghana

Abstract: HIV remains a major global health challenge, with approximately 48.1?million people affected worldwide and nearly 69% residing in sub-Saharan Africa. Regional…

Date: 2026-09-09

Long-term outcomes of eltrombopag plus cyclosporine A in eltrombopag-exposed patients with glucocorticoid-resistant or -dependent primary immune thrombocytopenia: a prospective, multicenter, single-arm, phase II study with extended follow-up

Abstract: Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by thrombocytopenia, and approximately 20-30% of patients are refractory to or dependent on…

Date: 2026-09-09