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Dynamic fibrinogen decline rate outperforms static admission values in predicting hematoma expansion in APL-related intracranial hemorrhage: a retrospective cohort study

Abstract: Intracranial hemorrhage (ICH) is the leading cause of early death in acute promyelocytic leukemia (APL). Current risk assessment relies on static coagulation parameters…

Date: 2026-10-07

Overall survival after relapse in high-risk neuroblastoma: an adjusted indirect comparison of post-relapse dinutuximab beta, historical controls, and relapse after first-line dinutuximab beta maintenance

Abstract: To compare overall survival (OS) in patients with relapsed neuroblastoma treated with dinutuximab beta (DB) after relapse with that of two comparator populations:…

Date: 2026-10-07

Capsaicin ameliorates diabetic nephropathy by targeted activation of GPX4 and inhibition of pyroptosis

Abstract: Capsaicin (CAP) is the primary pungent alkaloid found in chili peppers. The aim of this study is to screen for candidate therapeutic agents targeting the mitochondrial…

Date: 2026-10-07

Diabetic sarcopenia in clinical practice: expert consensus and usability evaluation of a novel screening and diagnostic algorithm

Abstract: Recently, an expert panel developed an algorithm for the screening, diagnosis, and staging of diabetic sarcopenia, a clinically relevant condition in the progression of…

Date: 2026-10-07

Independent and joint associations of reported household chemical product use and overweight/obesity with cardiovascular disease among older adults in China: a national cross-sectional study

Abstract: Household chemicals are common indoor exposures among older adults, but their association with cardiovascular disease (CVD) and whether the association varies according…

Date: 2026-10-07

Diagnostic utility of whole exome sequencing in children with suspected genodermatoses: a single-center retrospective study

Abstract: Genodermatoses are a group of monogenic inherited skin disorders characterized by marked genetic heterogeneity. Although the phenotype of many genodermatoses is readily…

Date: 2026-10-07

Copeptin and albumin in children with undernutrition

Abstract: Anthropometric assessment remains the cornerstone of the identification and classification of pediatric undernutrition, whereas the role of laboratory biomarkers is less…

Date: 2026-10-07

Perceived must see pediatric conditions vs. actual clinical exposure during an undergraduate pediatrics clerkship

Abstract: Undergraduate pediatric rotations aim to provide authentic exposure to core conditions. Programs often publish “must-see” lists, but student and doctor perceived…

Date: 2026-10-07

The diagnostic accuracy of ultrasonography in pediatric intussusception and its role in predicting the need for surgery

Abstract: Pediatric intussusception is a common gastrointestinal emergency requiring early diagnosis and appropriate treatment. Although ultrasonography (USG) is considered the…

Date: 2026-10-07

Receipt of needed care coordination and emergency department utilization among US children with chronic physical pain: a pooled analysis of the 2022–2024 National Survey of Children's Health

Abstract: Children with chronic physical pain often require complex, multidisciplinary services across medical, behavioral, and community systems. However, whether receipt of…

Date: 2026-10-07