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Genetic susceptibility and clinical validation of ICAM-5 in immune-mediated non-infectious uveitis

Abstract: To investigate genetically supported molecular factors associated with uveitis and to evaluate the clinical, transcriptomic, and retinal relevance of intercellular…

Date: 2026-10-06

Metabolic reprogramming of NK cells in chronic brucellar arthritis: role of the HIF-1?/mTOR axis

Abstract: Brucellar arthritis is the most common complication of brucellosis, and its chronic progression is closely associated with immune cell dysfunction. Natural killer (NK)…

Date: 2026-10-06

Association between the dietary index for gut microbiota and fracture prevalence among women aged 50?years and older: a NHANES-based study with a preliminary exploratory pilot analysis

Abstract: Gut microbiota has been implicated in bone metabolism, but whether a diet supporting gut microbial health is associated with fracture prevalence in older women remains…

Date: 2026-10-06

Nutritional indicator-based prediction model for esophagogastric variceal bleeding in cirrhosis using XGBoost and SHAP

Abstract: Malnutrition is common in cirrhotic patients and associated with poor prognosis, yet current models have suboptimal predictive performance for esophagogastric variceal…

Date: 2026-10-06

Altered OXPHOS potential in ascites immune cells is linked to CD4 T-cell exhaustion and a higher risk of spontaneous bacterial peritonitis in cirrhosis

Abstract: Ascites marks advanced cirrhosis and increases the risk of complications including SBP. Systemic inflammation in liver disease is well characterized, but the…

Date: 2026-10-06

Specific interventions as part of a quality improvement collaborative enhance care for ischemic stroke patients

Abstract: Adherence to guidelines for stroke care varies, despite evidence that managing fever, glycemia (sugar), and conducting swallowing screening (FeSS) reduces mortality and…

Date: 2026-10-06

Ravulizumab in neuromyelitis optica spectrum disorder: first clinical experience in Chile

Abstract: Neuromyelitis optica spectrum disorder (NMOSD) is a neuroimmunological astrocytopathy mediated by anti-aquaporin-4 (AQP4-IgG) antibodies that trigger…

Date: 2026-10-06

Long-term exposure to ambient air pollution and lipid profiles: a longitudinal study in a heavily industrialized region of northern China

Abstract: Dyslipidemia is an important modifiable risk factor for cardiovascular disease, and growing evidence suggests that long-term ambient air pollution exposure may adversely…

Date: 2026-10-06

Clinical, immunological, and radiological characteristics of pulmonary involvement in childhood-onset primary Sjögren’s syndrome: a single-center retrospective study

Abstract: To describe pulmonary involvement in childhood-onset primary Sjögren’s syndrome (cSS). This retrospective study included 17 children with cSS diagnosed at Jiangxi…

Date: 2026-10-06

Complement and immunoglobulin profiles in ANCA-associated vasculitis with renal involvement: a serotype-stratified analysis of disease activity and renal outcomes

Abstract: ANCA-associated vasculitis (AAV) is characterized by pauci-immune small-vessel inflammation driven predominantly by neutrophil activation, in contrast to…

Date: 2026-10-06