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Development and internal validation of a CatBoost–SHAP-guided nomogram for significant liver fibrosis in children with chronic hepatitis B

Abstract: Significant liver fibrosis can develop in children with chronic hepatitis B (CHB), yet liver biopsy is invasive and unsuitable for repeated assessment. We developed an…

Date: 2026-10-05

Blood pressure changes after stair climbing in busy and quiet outpatient clinic environments among Tanzanian adults: a randomised crossover study

Abstract: Blood pressure (BP) measured soon after activity may differ from later seated readings. We examined serial BP changes after stair climbing in busy and quiet outpatient…

Date: 2026-10-05

Deep learning-based prediction of HER2 status from breast diffusion-weighted MRI

Abstract: The accurate classification of human epidermal growth factor receptor 2 (HER2) status is very important for the diagnosis and treatment of breast cancer. However, the…

Date: 2026-10-05

Angiographic prevalence of occlusion myocardial infarction and the limited value of serial troponin in patients with non–ST-segment elevation acute coronary syndrome

Abstract: An estimated 25%–34% of patients with non–ST-segment elevation acute coronary syndrome (NSTE-ACS) are diagnosed with an occluded culprit artery during catheterization.…

Date: 2026-10-05

Age-indexed cumulative risk of high myopia estimated from axial length and early axial elongation: a 7-year school-based longitudinal cohort study

Abstract: To develop and validate age-indexed models estimating the cumulative risk of high myopia, defined as axial length (AL)???26.0?mm, using routinely collected ocular…

Date: 2026-10-05

Pulmonary hypertension optimal screening in interstitial lung disease (PHOS-ILD): a scoring system for the detection of pulmonary hypertension in patients with interstitial lung disease

Abstract: Pulmonary hypertension (PH) is a common comorbidity of interstitial lung disease (ILD). Timely detection may improve outcomes through implementation of PH specific…

Date: 2026-10-05

Latent classes and symptom network analysis of kinesiophobia in older adult patients with chronic obstructive pulmonary disease

Abstract: To identify the latent classes of kinesiophobia in older adult patients with chronic obstructive pulmonary disease (COPD), analyze the symptom network structure of…

Date: 2026-10-05

Development and internal validation of machine learning models for identifying suicidal behavior in inpatients with mood disorders

Abstract: Suicidal behavior (SB) is a major concern in mood disorders. Models developed from retrospective records are vulnerable to ambiguous targets, data leakage, and…

Date: 2026-10-05

Impact of traditional Chinese medicine combined with conventional therapies on the survival of patients with metastatic prostate cancer: a retrospective observational cohort study

Abstract: Traditional Chinese medicine (TCM) is incorporated into the long-term integrative management of advanced prostate cancer in China, but evidence linking treatment…

Date: 2026-10-05

A “family-school-hospital” collaborative oral health management model for preschool children: a prospective single-arm pre-post intervention study

Abstract: Early childhood caries (ECC) remains a global public health challenge, yet preschool children lack autonomy in health management and depend heavily on family and school…

Date: 2026-10-05