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Low-grade fibromyxoid and sclerosing epithelioid fibrosarcoma: distinct behaviour in the same spectrum of ultra-rare sarcomas

Abstract: Low-grade fibromyxoid sarcoma (LGFMS) and sclerosing epithelioid fibrosarcoma (SEF) represent a molecularly related spectrum of ultra-rare soft-tissue sarcomas…

Date: 2026-10-15

Targeting the MLN64/STARD3-cholesterol axis disrupts tight junction remodelling and attenuates gastric cancer aggressiveness

Abstract: Gastric cancer remains a major cause of cancer-related mortality, largely due to invasion, metastasis, and therapeutic resistance. Dysregulated cholesterol metabolism is…

Date: 2026-10-15

Long-term endocrine and reproductive outcomes in female adolescent and young adult survivors after hematopoietic stem cell transplantation for hematological malignancies during childhood or adolescence

Abstract: Cancer treatment during childhood and adolescence, particularly hematopoietic stem cell transplantation (HSCT), may adversely affect long-term reproductive and endocrine…

Date: 2026-10-15

Application of LLM combined with knowledge base in improving C-TIRADS grading of thyroid nodules

Abstract: This study used the unified text-based grading results of senior sonographers as the primary reference (this text benchmark is not pathological diagnostic gold standard)…

Date: 2026-10-15

Magnetocardiographic characteristics in patients with varying severity of obstructive sleep apnea syndrome

Abstract: Obstructive sleep apnea syndrome (OSAS) is an established risk factor for cardiovascular disease. Magnetocardiography (MCG) is an emerging non-invasive…

Date: 2026-10-15

Development and validation of a model of severe abdominal blast injury: characterization and hemostatic response

Abstract: To establish a stable porcine model of severe abdominal blast injury with massive hemorrhage and evaluate a novel hemostatic material (novel hydrogel bioadhesive) versus…

Date: 2026-10-14

A PBMC-based proof-of-principle framework for fit-for-purpose validation of flow cytometry assays in cell therapy development

Abstract: Cellular immunotherapy offers personalized therapeutic benefits but faces challenges such as manufacturing consistency and regulatory compliance. Validated analytical…

Date: 2026-10-14

Practice patterns in myeloma bone disease: a multi-center survey

Abstract: Bone disease is a common manifestation of multiple myeloma. Although anti-resorptive therapy is recommended by guidelines, implementation can be variable. We sought to…

Date: 2026-10-14

An ARG1-associated immunometabolic program in bone marrow PMN-MDSC-like cells in multiple sclerosis and experimental autoimmune encephalomyelitis

Abstract: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. Recent work indicates that bone-marrow hematopoietic niches sense…

Date: 2026-10-14

The diagnostic journey of fibrodysplasia ossificans progressiva: evidence from a national cohort of 114 patients

Abstract: Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare genetic disorder caused by gain-of-function variants in ACVR1 , characterized by congenital great-toe…

Date: 2026-10-14