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Neuron-specific expression of murine thyroid hormone transporters Mct8 and Oatp1c1 is dispensable for hippocampus-dependent neuronal functions

Abstract: Global absence of the thyroid hormone (TH) transporters monocarboxylate transporter 8 (Mct8) and organic anion transporting polypeptide 1c1 (Oatp1c1) in Mct8/Oatp1c1…

Date: 2026-03-17

Estimated small dense low-density lipoprotein cholesterol and hyperuricemia in diabetic patients

Abstract: Small dense low-density lipoprotein cholesterol (sdLDL-C) is a key driver of atherosclerotic cardiovascular disease risk. This study aims to investigate the relationship…

Date: 2026-03-17

A vision transformer-radiomics approach for enhanced chemotherapy outcome prediction in ovarian cancer

Abstract: Early prediction of chemotherapy response in ovarian cancer patients is essential for enabling personalized treatment strategies and improving clinical outcomes.…

Date: 2026-03-17

Predictors of ?50% volume reduction after radiofrequency ablation of uterine fibroids: a single-center retrospective case series in Romania

Abstract: The study aimed to explore the potential of routinely collected pre-procedural clinical and ultrasonographic parameters (age, classification, baseline fibroid volume,…

Date: 2026-03-17

Effects of esketamine combined with QLB in older frail patients with colorectal cancer surgery

Abstract: To investigate the effects of esketamine combined with quadratus lumborum block (QLB) on postoperative anxiety, depression, and cognitive function in frail older…

Date: 2026-03-17

Visual prognosis of Behçet’s uveitis patients in China and its associated factors

Abstract: Behçet’s disease (BD) is a chronic, relapsing, multisystem inflammatory disorder, with ocular involvement being a major cause of irreversible visual impairment. Behçet’s…

Date: 2026-03-17

GeneCytNet: an interpretable deep learning framework for rheumatoid arthritis classification and in silico cytokine perturbation modeling

Abstract: Rheumatoid arthritis (RA) is a heterogeneous autoimmune disease where cytokine-driven dysregulation of gene networks poses a significant challenge for accurate diagnosis…

Date: 2026-03-17

Effects of meteorological variability on the burden of musculoskeletal disorders among people aged 55 and above in the United States: a secondary analysis of the Global Burden of Disease Study 2021

Abstract: Older adults in high-income countries face an increasing burden of musculoskeletal (MSK) disorders. Although the belief that meteorological variations influence…

Date: 2026-03-17

Development and interpretable machine learning models for classification of pancreatic pseudocyst risk in acute pancreatitis

Abstract: Pancreatic pseudocysts (PPC) are a late local complication of acute pancreatitis (AP). Persistent PPC carry a high risk of severe outcomes. Existing models, which are…

Date: 2026-03-17

A cell line–derived, immune-competent neurospheroid model to study neuroinflammation and human brain disorders

Abstract: Three-dimensional (3D) human brain models have become indispensable tools to investigate neuroimmune interactions and inflammatory processes in the human central nervous…

Date: 2026-03-17