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Distinct diversity of skin cell populations of rhinophyma and hypertrophic scar illustrated by scRNA-seq

Abstract: The clinical manifestations and presentation of rhinophyma closely resemble those of hypertrophic scar tissue, both presenting as firm, fibrotic growths. Despite this…

Date: 2026-03-12

Spatial transcriptomic profiling reveals body site-specific inflammatory differences in psoriasis lesions

Abstract: Psoriasis is a common chronic inflammatory skin disease. Treatments lead to Q6 substantial improvement of most psoriasis plaques. However, it can be challenging to reach…

Date: 2026-03-12

A U-shaped association between sleep duration and depression in adult prescription opioid users

Abstract: The objective of this study was to investigate the correlation between sleep duration and depression in adult prescription opioid users. Data on adults who had recently…

Date: 2026-03-12

General anesthesia vs. non-general anesthesia for elderly stroke patients treated with mechanical thrombectomy

Abstract: This study aimed to compare the impact of general anesthesia (GA) versus non-GA on functional outcomes in elderly patients undergoing endovascular thrombectomy (EVT) for…

Date: 2026-03-12

Artificial intelligence-based endoscopic ultrasonography model for detecting the origin layer of gastric subepithelial lesions

Abstract: Gastric subepithelial lesions (SELs) are typically covered by intact mucosa, which challenges the determination of their layer of origin under conventional endoscopy.…

Date: 2026-03-12

Trends and disparities in skin malignant neoplasm mortality in the United States: a 22-year trend analysis based on CDC WONDER Data (1999-2020)

Abstract: Skin malignant neoplasms are common malignancies worldwide, with epidemiological characteristics showing significant geographical and demographic disparities. This study…

Date: 2026-03-11

Metabolic syndrome and the risk of perioperative ischemic stroke in non-cardiac surgery: a case-control retrospective study

Abstract: Perioperative ischemic stroke (PIS), although rare, is a devastating complication following surgery. Metabolic syndrome (MetS), also known as insulin resistance…

Date: 2026-03-11

The protective role of MDL-1 in sepsis-induced lung injury: insights from a murine CLP model

Abstract: The Myeloid DAP12-associating lectin-1 (MDL-1) serves as a pivotal pattern recognition receptor crucial for recognizing various pathogenic microorganisms and…

Date: 2026-03-11

Perceived HIV knowledge in the context of novel psychoactive substance use: evidence from a multi-city survey in Kazakhstan

Abstract: This study aims to investigate perceived HIV knowledge among NPS users in Kazakhstan and evaluate patient characteristics associated with higher perceived HIV knowledge.…

Date: 2026-03-10

Incidence and risk factors for postoperative nausea and vomiting following video-assisted thoracoscopic surgery: a prospective observational study

Abstract: Postoperative nausea and vomiting (PONV) is a common complication after general anesthesia, contributing to patient discomfort, adverse clinical outcomes, and increased…

Date: 2026-03-10