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Research Articles Search

Showing 280 of 147,163 result(s)
Machine learning model for predicting epidermal growth factor receptor expression status in breast cancer using ultrasound radiomics

Abstract: The epidermal growth factor receptor (EGFR) is a clinically important target, as its expression in patients with breast cancer influences both overall and disease-free…

Date: 2025-10-29

Modest radiation dose escalation for early-stage anal cancer: cancer control and toxicity outcomes

Abstract: The optimal dose for patients with early-stage squamous cell carcinoma of the anus (SCCA) is unknown. We aimed to evaluate the impact of modest dose escalation (54 Gray…

Date: 2025-10-29

Machine learning-based predictive model for immune checkpoint inhibitors response in gastrointestinal cancers

Abstract: Gastrointestinal (GI) cancers present significant clinical challenges characterized by dismal survival outcomes and suboptimal prognoses. Currently, only partial…

Date: 2025-10-29

Gustave Roussy immune score as an independent prognostic factor for treatment response and survival in advanced renal cell carcinoma treated with nivolumab in second-line and beyond

Abstract: Metastatic renal cell carcinoma (mRCC) represents a significant challenge due to variable patient outcomes despite advancements in treatment. Nivolumab, a programmed…

Date: 2025-10-29

A robust stacked neural network approach for early and accurate breast cancer diagnosis

Abstract: Timely and accurate diagnosis of breast cancer remains a critical clinical challenge. In this study, we propose Stacked Artificial Neural Network (StackANN), a robust…

Date: 2025-10-29

The relationship between changes in alcohol consumption and hepatic steatosis among alcohol consumers: a large-scale population-based Biobank study

Abstract: The relationship between changes in alcohol consumption and hepatic steatosis among alcohol consumers remains poorly understood. This study aimed to evaluate the…

Date: 2025-10-29

Exploring the carcinogenic potential of bisphenol A in lung adenocarcinoma: molecular mechanisms, key gene insights, and immune microenvironment impacts

Abstract: Bisphenol A (BPA) is an endocrine-disrupting chemical that may contribute to cancer development. However, its role in lung adenocarcinoma (LUAD) remains poorly…

Date: 2025-10-29

Changes in the malignant female reproductive system tumors disease spectrum at the Beijing obstetrics and gynecology hospital in the past 60?years

Abstract: This study aimed to evaluate the epidemiological trends in the incidence, age distribution, and pathological types of malignant female reproductive system tumors over…

Date: 2025-10-29

A model structure for describing uncertainties in benefit-risk assessment of oncology drug applications

Abstract: The European Medicines Agency (EMA) uses structured reports to communicate the scientific review of drug applications. A European Public Assessment Report (EPAR) is…

Date: 2025-10-29

Interpretable machine-learning-based prediction of postpartum haemorrhage in normal vaginal births in Shanghai, China

Abstract: Postpartum haemorrhage is the most common complication associated with vaginal birth and a principal cause of maternal mortality. While clinical guidelines suggest that…

Date: 2025-10-29