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Association between frailty index and all-cause mortality in hospitalized elderly patients with osteoporotic fractures: a retrospective cohort study

Abstract: Osteoporotic fractures (OPF) represent a significant health concern among the elderly population. Frailty, a prevalent condition in this demographic, can be evaluated…

Date: 2025-11-21

LncRNA ELDR promotes bladder cancer malignant progression by regulating the miR-1343-3p/ TRIM44 axis

Abstract: Bladder cancer (BCa) is one of the most prevalent genitourinary malignancies with high recurrence worldwide. A lack of reliable prognostic biomarkers and effective…

Date: 2025-11-21

Development and validation of an osteoporosis risk prediction model incorporating nighttime eating exposure

Abstract: Osteoporosis (OP) is a global bone metabolic disease, and its incidence continues to rise with the intensifying aging of the population. In recent years,…

Date: 2025-11-21

Association between serum total cholesterol levels and Crohn’s clinical disease severity: a retrospective cross-sectional study

Abstract: This retrospective cross-sectional study aimed to investigate the relationship between serum total cholesterol (TC) levels and the clinical activity of Crohn’s disease…

Date: 2025-11-21

Risk factors and impact on outcomes of high-density shadow on immediate cerebral CT after successful interventional recanalization in acute ischemic stroke with large vessel occlusion

Abstract: To explore the risk factors, classification, relation with hemorrhage and clinical significance of high-density shadow on immediate cerebral CT in patients with large…

Date: 2025-11-21

No impact of intravenous thrombolysis on post thrombectomy transcranial Doppler pulsatility index

Abstract: While transcranial Doppler (TCD) studies are beneficial in evaluating macrovascular recanalization post mechanical thrombectomy (MT), they may have a role in estimating…

Date: 2025-11-21

NETs promote invasive behavior of fibroblast-like synoviocytes through GPIb? in rheumatoid arthritis

Abstract: Neutrophil extracellular traps (NETs) have been implicated in rheumatoid arthritis (RA) pathogenesis, yet their effects on fibroblast-like synoviocytes (FLS) remain…

Date: 2025-11-21

Coordinated kinetics of humoral, T-cell, and cytokine responses to SARS-COV-2 in West African healthcare workers: a multicenter longitudinal study in university hospitals of Abidjan, Côte d’Ivoire

Abstract: Healthcare workers in resource-limited settings are frequently exposed to SARS-CoV-2, often with incomplete vaccine coverage. Yet, their adaptive immune responses remain…

Date: 2025-11-21

Suppression of NK cell-mediated immunosurveillance by IL-35 drives tumor progression in EGFR-mutant non-small cell lung cancer

Abstract: Interleukin-35 (IL-35) is an added member of the IL-12 heterodimeric cytokine family, composed of two subunits: EBI3 and P35 subunits, implicated in tumor immune…

Date: 2025-11-20

Integration of intratumoral/peritumoral radiomics and deep learning for predicting overall survival in non-small cell lung cancer patients: a multicenter study

Abstract: Prognostic assessment of non-small cell lung cancer (NSCLC) relies on TNM staging, yet tumor heterogeneity limits its accuracy. This study aimed to develop a model for…

Date: 2025-11-20