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Establishment of prognostic signature based on neutrophil extracellular traps-related genes in acute myeloid leukemia: a bioinformatics analysis

Abstract: Acute myeloid leukemia (AML) is a hematological malignancy with a high incidence of febrile neutropenia during the first two treatment cycles. This study aims to develop…

Date: 2025-10-24

Sleep quality during preparation for RAI: recombinant TSH vs. levothyroxine withdrawal

Abstract: Patients with differentiated thyroid cancer (DTC) suffer from impaired sleep quality, which may be further impaired after radioactive iodine (RAI) treatment. The…

Date: 2025-10-24

Interplay of endocrine and psychological factors in IVF/ICSI outcomes: a prospective cohort analysis

Abstract: Infertility poses considerable challenges to both the endocrine system and psychological well-being of affected women. In particular, those undergoing Assisted…

Date: 2025-10-24

Single-cell RNA sequencing analysis reveals the critical role of fibroblasts in aortic progeria-associated vascular remodeling in Hutchinson-Gilford progeria syndrome mice

Abstract: Patients with Hutchinson-Gilford progeria syndrome (HGPS) typically succumb to cardiovascular diseases in their teens. Although fibroblasts have been implicated in the…

Date: 2025-10-24

Comparative real-world effectiveness and safety of biologics and JAK inhibitors in atopic dermatitis: short- and medium-to-long-term analysis from a regional healthcare network in southern Spain

Abstract: Biologics and Janus kinase (JAK) inhibitors have expanded treatment options for moderate-to-severe atopic dermatitis (AD), but comparative real-world data remain…

Date: 2025-10-24

Allergy diagnostic performance of FastCheckPOC 20 Atopy

Abstract: The increasing prevalence of allergic diseases, along with their diagnosis and treatment, presents a growing challenge in health care. To reduce this burden, a highly…

Date: 2025-10-24

Screened prevalence of trichotillomania and its association with self-esteem among Saudi medical students: a cross-sectional study

Abstract: Trichotillomania is a chronic psychiatric syndrome characterized by an uncontrollable urge to pull out one’s hair. The current diagnostic criteria for Trichotillomania…

Date: 2025-10-24

Wavering between life and death: a qualitative study into the perceived causes and needs of persons with persistent suicidality

Abstract: One of the key issues in the current knowledge base on persistent or chronic suicidality is the discrepancy between the extensive experiential knowledge embedded in…

Date: 2025-10-24

Changes in human tear metabolome following topical 0.05% cyclosporine A on primary Sjögren’s syndrome

Abstract: This study aimed to investigate changes in the tear metabolome and the therapeutic impact of 0.05% cyclosporine A (CsA) eye drops in patients with dry eye disease (DED)…

Date: 2025-10-24

NF-?B/IL-6 axis drives impaired corneal wound healing in aqueous-deficient dry eye

Abstract: Dry eye disease (DED) commonly leads to compromised corneal epithelial integrity and chronic ocular surface inflammation; however, the precise molecular mechanisms…

Date: 2025-10-24