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The impact of memory training on abstinence among individuals with alcohol use disorder

Abstract: Chronic excessive alcohol consumption is associated with cognitive deficits. Patients with cognitive impairment, particularly memory deficits, may have difficulties in…

Date: 2025-12-12

Deep learning, deeper relief: pipeline toward tailored analgesia for experimental animal models

Abstract: Effective pain management in animal models is crucial for maintaining ethical and scientific integrity. However, commonly used analgesics may affect immune responses and…

Date: 2025-12-12

Organosilicone double-long-chain diquaternary ammonium salt acts as a biofilm scavenger to ameliorate colitis induced by dextran sulfate sodium salt

Abstract: The treatment of ulcerative colitis (UC) remains challenging due to limited efficacy and significant side effects. Organosilicone Double-Long-Chain Diquaternary Ammonium…

Date: 2025-12-12

Identification and validation of biomarkers related to centrosome replication in ulcerative colitis based on bulk transcriptome, single-cell RNA sequencing and experiments

Abstract: Ulcerative colitis (UC) is a complex chronic inflammatory disease. Centrosome amplification (CA) has been implicated in UC pathogenesis, but its mechanistic role remains…

Date: 2025-12-12

Association between systemic immune-inflammation index at admission and post-stroke depression in patients with acute ischemic stroke

Abstract: Post-stroke depression (PSD) is one of the most common neuropsychiatric complications among stroke survivors, with a substantial impact on functional recovery and…

Date: 2025-12-12

Integrated analysis of the relationship between metabolic pathways and immune infiltration in rheumatoid arthritis

Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovitis and systemic inflammation. Growing evidence highlights the critical role…

Date: 2025-12-12

Central venous catheter care and the healthcare–environment interface: outcomes of a quality improvement initiative in a resource-constrained ICU

Abstract: Central line-associated bloodstream infections (CLABSI) are major indicators of healthcare quality and patient safety, particularly in resource-constrained intensive…

Date: 2025-12-12

Low complement items play different roles on the classification performance of SLICC-2012, EULAR/ACR-2019, and SLERPI

Abstract: This study aimed to explore the association of low complement items with the performance of the systemic lupus erythematosus (SLE) classification criteria. This study…

Date: 2025-12-12

RUNX1-FPDMM in families with mild thrombocytopenia and platelet function anomalies: a case series

Abstract: RUNX1-familial platelet disorder with associated myeloid malignancy (RUNX1-FPDMM) is caused by heterozygous germline variants of RUNX1 . With the broader application of…

Date: 2025-12-11

Effects of short-term very low-calorie diet on metabolic profile in patients with metabolic syndrome

Abstract: Accumulating evidence indicates that dietary modifications confer beneficial effects on metabolic syndrome (MetS). In clinical practice, short-term very low-calorie…

Date: 2025-12-11