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Development and validation of a nomogram for predicting intrapartum fever in parturients with epidural analgesia

Abstract: Intrapartum fever is a common complication during labor that may adversely affect both maternal and neonatal outcomes. However, its underlying multifactorial etiology…

Date: 2025-10-06

The effect of esketamine on perioperative neurocognitive dysfunction in elderly patients undergoing gastrointestinal tumor surgery: a randomized double-blind controlled study

Abstract: We aimed to whether esketamine induction and maintenance of general anesthesia could reduce the incidence of perioperative neurocognitive dysfunction (PND) in elderly…

Date: 2025-10-06

State-dependent changes in peak alpha frequency during visual engagement in children with and without autism spectrum disorder

Abstract: Peak alpha frequency (PAF) is a neurophysiological marker of cortical maturation and cognitive function. We aimed to examine PAF reactivity to a visually engaging…

Date: 2025-10-06

Cognition-associated gray matter volume alterations in long-COVID show sex-specific patterns

Abstract: The long-term effects of the coronavirus disease 2019 (COVID-19) are a major concern in today’s society, with cognitive impairment being an important manifestation.…

Date: 2025-10-06

3D histological mapping of hippocampal subfields: a comparative study in patients with schizophrenia and healthy controls

Abstract: Hippocampal deviations are a hallmark of schizophrenia, yet their regional specificity remain unclear. Neuroimaging studies have reported smaller volumes for each…

Date: 2025-10-06

The mediating effect of serum cortisol between stigma and post-stroke depression in stroke patients

Abstract: This study aimed to explore the mediating effect of serum cortisol on the relationship between stigma and post-stroke depression (PSD) in patients with acute ischemic…

Date: 2025-10-06

Health-related quality of life outcomes from KEYNOTE-412: chemoradiotherapy with or without pembrolizumab in participants with head and neck squamous cell carcinoma

Abstract: The health-related quality of life (HRQoL) of patients with locally advanced head and neck squamous cell carcinoma (LA HNSCC) is impacted by both disease- and…

Date: 2025-10-06

Administration of statins is correlated with favourable prognosis in lung cancer patients receiving immune checkpoint inhibitors

Abstract: Statins are commonly used for cardiovascular diseases and recent studies have supported their anti-cancer role in numerous human malignancies. This study aims to…

Date: 2025-10-06

Trends in liver cancer burden in China and G20: a comparative analysis using GBD 2021

Abstract: To compare liver cancer trends and risk factors in China with those in G20 countries (1990–2021) to inform prevention and resource allocation. GBD 2021 data for liver…

Date: 2025-10-06

Homologous recombination deficiency in breast cancer: genomic characteristics, clinical implications, and predictive value in neoadjuvant therapy

Abstract: Homologous recombination deficiency (HRD) significantly influences breast cancer development. HRD-positive breast cancer is more sensitive to DNA-targeting cytotoxic…

Date: 2025-10-06