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Research Articles Search

Showing 990 of 147,163 result(s)
Surgery versus neoadjuvant chemoradiotherapy followed by surgery in locally advanced gastrointestinal tract cancers

Abstract: Gastrointestinal tract cancer is still prevalent in the world. Localized GI cancer treatment has greatly relied on surgery, even for locally advanced diseases. The goal…

Date: 2025-10-01

Simultaneous profiling of the blood and gut T and B cell repertoires in Crohn’s disease and symptomatic controls illustrates tissue-specific alterations in the immune repertoire of individuals with Crohn’s disease

Abstract: Crohn’s disease (CD) is a clinical subset of inflammatory bowel disease that is characterized by patchy transmural inflammation across the gastrointestinal tract.…

Date: 2025-10-01

Novel RNA-methylase HNRNPC promotes gastric cancer tumorigenesis by triggering the lactate-induced ferroptosis resistance

Abstract: Emerging evidence gradually indicates that lactate and iron-induced cell death plays important role in gastric cancer (GC) progression. Here, this study focused on the…

Date: 2025-10-01

Dynamic stability of gut microbiota in elite volleyball athletes: microbial adaptations during training, competition and recovery

Abstract: To examine how different weekly training and competition schedules influence gut microbiota composition in elite volleyball players, investigating the relationship…

Date: 2025-10-01

TRP-related gene signatures predict survival and the immune microenvironment in rectal cancer: a comprehensive bioinformatics study

Abstract: The pathogenesis of rectal cancer (RC) involves a variety of biological mechanisms; however, the prognostic significance of temperature-sensitive receptor (TRP) channels…

Date: 2025-10-01

Developing models for the diagnosing of ulcerative colitis and prognosis of anti-TNF-? non-response based on neutrophil extracellular trap-associated genes

Abstract: Neutrophil extracellular traps (NET) play a pivotal role in the pathogenesis of ulcerative colitis (UC) and may contribute to the impaired response to anti-tumor…

Date: 2025-10-01

Malignant epithelia cells-derived spermine induces APOE+ macrophages to suppress tumor immunity in adenocarcinoma of the esophagogastric junction

Abstract: Adenocarcinoma of the esophagogastric junction (AEG) is increasingly recognized as a distinct gastrointestinal tumor type with a poor prognosis. However, the mechanisms…

Date: 2025-10-01

Adverse events of ursodeoxycholic acid: a real-world pharmacovigilance study using FAERS (2004–2023)

Abstract: Ursodeoxycholic acid (UDCA) has been widely used in the treatment of hepatobiliary disorders and its clinical application is more and more extensive. However, to our…

Date: 2025-10-01

Bioinformatics-based analysis and experimental validation of PANoptosis-related biomarkers and immune infiltration in diabetic nephropathy

Abstract: Diabetic nephropathy (DN) is a frequent and serious microvascular complication of diabetes. PANoptosis is a novel mode of cell death that encompasses apoptosis, necrosis…

Date: 2025-10-01

Management of type I gastric-neuroendocrine tumors: the less the better?

Abstract: Type I gastric neuroendocrine tumors (gNETs) are known for their favorable prognosis. We aimed to present a real-life experience at a tertiary referral center.…

Date: 2025-10-01