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Research Articles Search

Showing 980 of 147,163 result(s)
Identification of amino acid metabolism-related gene Leucyl-tRNA synthetase 1 (LARS1) as a potential prognostic and therapeutic target in hepatocellular carcinoma

Abstract: Amino acid metabolism plays a critical role in tumorigenesis in hepatocellular carcinoma (HCC). Thus, we explore the amino acid metabolic profile in HCC to construct…

Date: 2025-10-01

A comparison of trends in the incidence of non-alcoholic steatohepatitis-related liver cancer in the BRICS countries from 1990 to 2021, alongside projections for the next 15 years

Abstract: Despite the ongoing rise in the global burden of non-alcoholic steatohepatitis-related liver cancer (NALC), systematic analyses and long-term trend projections of the…

Date: 2025-10-01

Mapping artificial intelligence adoption in hepatology practice and research: challenges and opportunities in MENA region

Abstract: Artificial intelligence (AI) is increasingly relevant to hepatology, yet real-world adoption in the Middle East and North Africa (MENA) is uncertain. We assessed…

Date: 2025-10-01

Single-cell RNA profiling of colorectal granular-type laterally spreading tumor uncovers progression trajectory toward carcinoma and transcriptional signatures favoring lateral morphogenesis

Abstract: Colorectal laterally spreading tumors (LSTs) are defined as non-protruding neoplasms exceeding 10 mm in diameter that grow primarily along the intestinal wall. The…

Date: 2025-10-01

Latent profiles and associated factors of workplace violence among nurses in tertiary hospitals: a cross-sectional study

Abstract: Workplace violence (WPV) is a significant occupational hazard that threatens nurses’ psychological well-being and professional stability. Although prior studies have…

Date: 2025-10-01

The IBD-disk accurately assesses disability and psychological burden at IBD diagnosis and predicts adverse outcomes in both UC and Crohn’s disease during the first year of treatment: a prospective observational cohort study

Abstract: Inflammatory bowel disease (IBD) is linked with increased prevalence of mental health disorders (MHD), particularly anxiety and depression. How this influences treatment…

Date: 2025-10-01

Gain-of-function mutations in KATP channel subunits compromise colonic tight junction integrity and epithelial homeostasis in murine models of Cantú syndrome

Abstract: Cantú syndrome (CS) is a rare genetic disorder caused by gain-of-function (GOF) mutations in the KCNJ8 (Kir6.1) or ABCC9 (SUR2) subunits of ATP-sensitive potassium…

Date: 2025-10-01

Circulatory cathepsin K as biomarkers in older adults with sarcopenia: a case-control study

Abstract: This study explores the relationship between circulating cathepsin K (CatK) and cathepsin D (CatD) levels and sarcopenia in older adults. This case-control study…

Date: 2025-10-01

A real-world study of polyenyl phosphatidylcholine in the management of patients with metabolic dysfunction-associated fatty liver disease in China clinical practice

Abstract: Metabolic dysfunction-associated fatty liver disease (MAFLD) is highly prevalent in China. Clinical evidence supporting the role of polyenyl phosphatidylcholine (PPC) in…

Date: 2025-10-01

GLP-1 receptor agonist increase retained gastric contents on EGD and same-day colonoscopy reduces this risk

Abstract: With the rise in glucagon-like peptide 1 receptor agonist (GLP-1RA) medication usage for Type 2 diabetes mellitus and weight loss, concerns have been raised regarding…

Date: 2025-10-01