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Inflammatory cytokines as predictors of therapeutic response to valproate in patients with comorbid alcohol use disorder and bipolar disorder

Abstract: Alcohol use disorder (AUD) is a chronic condition commonly associated with bipolar disorder (BD). We previously reported that valproate (VPA) can decrease drinking in…

Date: 2026-09-24

Effects of psychedelic drug use on neurocognitive function and the psychological and social domains of quality of life: an international online study

Abstract: The past few decades have seen a revived interest in psychedelic-assisted and ketamine-assisted therapy for mental health disorders, but data concerning the acute,…

Date: 2026-09-24

Performance evaluation of mainstream large language models in cataract science popularization Q&A: a comparative study of readability, quality, and educational suitability

Abstract: Cataract is one of the main causes of visual impairment and reversible blindness worldwide, and it mainly affects the elderly population. Clinically accurate and…

Date: 2026-09-24

MoCA-screen-positive status differs across intraocular pressure subtypes of primary open-angle glaucoma

Abstract: Cognitive vulnerability may differ across intraocular pressure-defined subtypes of primary open-angle glaucoma (POAG), but visually dependent cognitive-screening tasks…

Date: 2026-09-24

Ocular injuries caused by Japanese black bears: a 10-year retrospective analysis of severity and clinical outcomes

Abstract: Although bear-related injuries are increasing in Japan, ocular trauma associated with Japanese black bear ( Ursus thibetanus japonicus ) attacks has rarely been…

Date: 2026-09-24

Epidemiological study of dry eye disease in Gansu Province based on mathematical modeling: analysis of regional population characteristics and identification of risk factors

Abstract: To investigate the epidemiological characteristics of dry eye disease (DED) in Gansu Province, examine the associations between regional population features and DED, and…

Date: 2026-09-24

Association between leukocyte-derived inflammatory biomarkers and diabetic retinopathy progression in patients with type 2 diabetes mellitus

Abstract: To characterize changes in leukocyte-based inflammatory biomarkers in patients with diabetic retinopathy (DR) progression, using the DR non-progression group as a…

Date: 2026-09-24

Factors associated with the self-awareness of fall risk among older patients with osteoporosis: a cross-sectional analysis

Abstract: This study aimed to investigate the current status and influencing factors of self-awareness of fall risk among older patients with osteoporosis, and to provide a…

Date: 2026-09-24

Co-recorded conditions in ischemic and hemorrhagic stroke: a 20-year national analysis of 598,186 natural deaths with machine learning

Abstract: The purpose of this study was to characterize the co-occurrence patterns of co-recorded conditions in ischemic and hemorrhagic stroke and identify co-recorded conditions…

Date: 2026-09-24

Diagnostic utility of targeted flow cytometry in genetically confirmed inborn errors of immunity: a 20-year single-center experience

Abstract: Inborn errors of immunity (IEIs) are a heterogeneous group of genetic disorders in which timely diagnosis is essential for appropriate treatment and improved clinical…

Date: 2026-09-24