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ZBP1 contributes to IFN-?-induced PANoptosis-related skeletal muscle cell injury in dermatomyositis

Abstract: Dermatomyositis (DM) is a systemic autoimmune disease characterized by cutaneous manifestations and inflammatory skeletal muscle injury. Dysregulated type I interferon…

Date: 2026-09-24

Multimodal characterization of HLA-G expression across solid tumors reveals transcript-protein discordance and implications for immunotherapy targeting

Abstract: Human leukocyte antigen-G (HLA-G) is a non-classical major histocompatibility complex class I molecule that functions as an immune checkpoint via inhibitory receptors…

Date: 2026-09-24

Prognostic significance of co-expression of c-MET and EGFR in locally advanced and metastatic gastric cancer: a retrospective cohort study

Abstract: Gastric cancer (GC) remains a leading cause of cancer-related mortality globally. While molecular targeted therapies against HER2 and PD-L1 have advanced, the role of…

Date: 2026-09-24

Effect of BMI-stratified management based on the meridian-lymph axis theory on lower extremity lymphedema after gynecological cancer surgery: a randomized controlled trial

Abstract: Lower-extremity lymphedema (LEL) is a chronic complication after gynecological cancer surgery. Obesity may aggravate lymphatic dysfunction and reduce the effectiveness…

Date: 2026-09-24

Advanced endometrial cancer in the gulf cooperation council: a modified-Delphi consensus on unmet needs, molecular testing, and treatment sequencing

Abstract: Advanced endometrial cancer (EC), including primary unresectable stage III–IV, metastatic, and recurrent disease, is an increasing clinical challenge in the Gulf…

Date: 2026-09-24

Sublingual microcirculation-derived glycocalyx barrier impairment independently predicts progression of asymptomatic left ventricular diastolic dysfunction in elderly Chinese adults

Abstract: Coronary microvascular dysfunction has been confirmed to be associated with cardiac diastolic dysfunction (DD). The endothelial glycocalyx (EG) is essential for…

Date: 2026-09-24

Diagnostic value of bronchoalveolar lavage fluid cytokine and lymphocyte profiles for lower respiratory tract infections in patients with lymphoma

Abstract: Distinguishing lower respiratory tract infections (LRTIs) from noninfectious pulmonary infiltrates (NPIs) in patients with lymphoma is challenging. We assessed the…

Date: 2026-09-23

Nutritional status, body composition and bone health in treatment-naïve transgender and gender-diverse adolescents

Abstract: Gonadotropin-releasing hormone analogue (GnRHa)-induced gonadal suppression is an established component of gender-affirming care for transgender and gender-diverse (TGD)…

Date: 2026-09-23

Clinical features, comorbidities, and therapeutic outcomes of Cushing syndrome: a retrospective multicenter study from Saudi Arabia

Abstract: Cushing syndrome (CS) is associated with significant morbidity and mortality, but data from the Middle East, including Saudi Arabia, are limited. This study aimed to…

Date: 2026-09-23

Clinical profile, reported triggers, and comorbidity pattern in children and adolescents with atopic dermatitis: a cross-sectional study from Fujian, China

Abstract: Detailed clinical descriptions of paediatric atopic dermatitis from southern China are scarce; available Chinese data are largely modelled burden estimates or laboratory…

Date: 2026-09-23