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Association between a stepwise health education model based on evidence-based practice and self-care behaviors of patients with chronic heart failure: a single-center retrospective cohort study

Abstract: This study aims to investigate the association between a stepwise health education model based on evidence-based practice (EBP) and self-care behaviors, cardiac function…

Date: 2026-10-14

Microvascular resistance reserve: insights into discordant resting and hyperemic epicardial coronary physiology

Abstract: Discordance between resting and hyperemic epicardial physiology is commonbut mechanistically unclear. Microvascular resistance reserve (MRR), a novelindex of…

Date: 2026-10-14

Body mass index, diabetes, inflammation and survival in COVID-19: a retrospective study evaluating the obesity paradox in an urban hospital center

Abstract: Severe coronavirus disease 2019 (COVID-19) is associated with increased morbidity and mortality, particularly among patients with comorbidities such as diabetes and…

Date: 2026-10-13

Lipid metabolism-related inflammatory indices and diabetic kidney disease in patients with type 2 diabetes mellitus: a cross-sectional study

Abstract: Improving the prognosis of diabetic kidney disease (DKD) requires early diagnosis and treatment. This study examined the associations of lipid metabolism-related…

Date: 2026-10-13

Preventive administration of Bifidobacterium animalis subsp. lactis HEM20–01 attenuates the development of atopic dermatitis-like inflammation in mice, along with gut microbial and succinate alterations

Abstract: Atopic dermatitis (AD) is a chronic inflammatory skin disorder frequently accompanied by gut dysbiosis and neurobehavioral comorbidities, but the microbial metabolites…

Date: 2026-10-13

Psychological stress documentation and subsequent risk of chronic inflammatory skin diseases: a large-scale real-world cohort study

Abstract: Chronic inflammatory skin diseases (CISD) affect 20-25% of the population. Psychological stress is considered a modifiable risk factor, yet epidemiologic evidence…

Date: 2026-10-13

Clinical factors associated with septic shock in pediatric invasive meningococcal disease: a retrospective study from two tertiary hospitals in Chile, 2009–2025

Abstract: Invasive meningococcal disease (IMD) remains a primary etiology of bacterial meningitis and a cause of long-term neurological sequelae in children. We aimed to describe…

Date: 2026-10-13

Serum insulin-like growth factor-1 is lower in children with type 1 and type 2 diabetes mellitus than in a non-diabetic comparison group after adjustment for age and sex: a cross-sectional study

Abstract: Few studies have compared insulin-like growth factor-1 (IGF-1) in children with type 1 (T1DM) and type 2 diabetes (T2DM) against a shared non-diabetic reference group.…

Date: 2026-10-13

Age-specific reference intervals for serum IgG, IgA, and IgM in healthy Brazilian children and adolescents

Abstract: Serum immunoglobulin reference intervals vary by age, ethnicity, and environment, limiting the clinical utility of international guidelines for Brazilian pediatric…

Date: 2026-10-13

A nomogram integrating ultrasound features of the primary tumor and axillary lymph nodes with clinicopathological factors to predict high axillary lymph node burden in invasive breast cancer

Abstract: To develop and validate a nomogram that integrates ultrasound features of the primary tumor and axillary lymph nodes with lymphovascular invasion (LVI) for early…

Date: 2026-10-13