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Benchmarking the performance of large language models on medical genetics questions: a comparative evaluation of GPT-5.1, Gemini Pro 3, and Claude Opus 4.5

Abstract: This study benchmarks the performance of three state of the art large reasoning models comprising GPT 5.1, Gemini Pro 3, and Claude Opus 4.5 by evaluating their…

Date: 2026-10-13

Speech-based identification of suicide risk in patients with MDD: model development and 4-week follow-up validation

Abstract: Patients with major depressive disorder (MDD) have a substantially higher risk of suicide than the general population, whereas current suicide risk identification mainly…

Date: 2026-10-13

ADAM17-mediated CD16 shedding drives monocyte subset misclassification in ex vivo immunological assays

Abstract: Human monocytes are classified as classical (CD14++CD16?), intermediate (CD14++CD16+), and non-classical (CD14+CD16++) subsets, but CD16 stability during ex vivo assays…

Date: 2026-10-13

Reported infant safety information and perinatal service engagement among birth partners and co-parents. An exploratory cross-sectional survey at a large UK teaching hospital

Abstract: Infant mortality in the United Kingdom is higher in areas of socioeconomic deprivation and within several minority ethnic groups. Preventive strategies rely in part on…

Date: 2026-10-13

A laboratory-based selected logistic model for early prediction of 28-day mortality in patients with septic shock

Abstract: Early risk stratification in septic shock requires transparent models based on variables available soon after clinical diagnosis of septic shock. We reanalysed a…

Date: 2026-10-13

Systemic inflammatory response index as an independent predictor of all-cause mortality in patients receiving maintenance hemodialysis: a retrospective cohort study

Abstract: Chronic kidney disease (CKD) represents a major global public health burden, with affected individuals facing substantially elevated risks of morbidity, mortality, and…

Date: 2026-10-13

Primary care reform and concurrent changes in the regional distribution and equity of the ministry of health family medicine workforce in Saudi Arabia: a descriptive longitudinal analysis, 2014–2022

Abstract: Saudi Arabia's Vision 2030, with family medicine positioned as the organising specialty of primary care. Whether this transformation has translated into a more equitable…

Date: 2026-10-13

Development and validation of a simple clinical prediction model for post-stroke seizures in critically ill patients: a multicenter retrospective cohort study

Abstract: Post-stroke seizures (PSS) are common in critically ill stroke patients, but ICU-specific risk prediction tools are lacking, and the independent impact of PSS on…

Date: 2026-10-13

The predictive model of intra-arrest blood markers for the sustained return of spontaneous circulation in patients with out-of-hospital cardiac arrest

Abstract: This study aimed to investigate the predictive value of intra-arrest blood markers, including blood routine, blood biochemistry, and coagulation profile, during…

Date: 2026-10-13

A model for prediction of a twin live birth following in vitro fertilization–embryo transfer in women of advanced age

Abstract: The aim of this study was to construct a model for prediction of the probability of a twin live birth in women of advanced age in vitro fertilization and embryo transfer…

Date: 2026-10-13