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Language-dependent variation in observed mechanistic performance of web-enabled large language models across myeloid–mucosal immune contexts: a blinded expert evaluation

Abstract: To determine whether observed mechanistic performance of web-enabled large language model (LLM) responses differs across response languages under deployed web conditions…

Date: 2026-09-15

Vitamin D status in patients with arthritis and osteoporosis: a comparative analysis of inpatient and outpatient cohorts

Abstract: Vitamin D deficiency is a global health issue linked to musculoskeletal disorders, including osteoporosis and arthritis. Despite its critical role in bone and immune…

Date: 2026-09-15

Public-facing health information on achalasia generated by large language models: a multidimensional comparative study

Abstract: Large language models (LLMs) are increasingly used by the public to obtain health information, but their ability to provide reliable information for achalasia remains…

Date: 2026-09-15

Epidemiological trends and risk factors of early-onset colorectal cancer in the founding BRICS countries, 1990–2023, with projections to 2050

Abstract: Early-onset colorectal cancer (EOCRC) is increasing globally and represents an emerging public health concern. The BRICS countries (Brazil, Russia, India, China, and…

Date: 2026-09-15

EPS deficiency aggravates intestinal mucosal inflammation and dysbiosis through disrupting macrophage polarization balance in ulcerative colitis

Abstract: Ulcerative colitis (UC) is a chronic, immune-mediated inflammatory bowel disorder, and macrophages are essential for maintaining intestinal mucosal balance during UC.…

Date: 2026-09-15

ASNS-dependent asparagine availability supports intestinal ILC2 responses and type 2 immunity under nutrient-limited conditions

Abstract: Nutrient availability critically governs group 2 innate lymphoid cell (ILC2) function and type 2 immunity. Here, we identify the non-essential amino acid asparagine…

Date: 2026-09-15

Transcriptomics-based analysis of muscle injury mechanism mediated by inflammatory imbalance in the Duchenne muscular dystrophy muscle microenvironment

Abstract: Duchenne muscular dystrophy (DMD) is a hereditary neuromuscular disease characterized by progressive myofiber injury, chronic inflammatory response, and persistent…

Date: 2026-09-15

Preoperative depressive symptoms as a marker of postoperative delirium risk in older adults: a prospective cohort study in spine surgery

Abstract: Postoperative delirium (POD) is a frequent perioperative complication in older adults and is associated with delayed recovery and adverse cognitive outcomes. We…

Date: 2026-09-15

Long-term mental health and quality of life in patients after cervical artery dissection

Abstract: Most patients with Cervical Artery Dissection (CeAD) experience good long-term functional outcome. Little is known about long-term psychological sequelae in these…

Date: 2026-09-15

Gray matter atrophy mediates the association between cerebral hypometabolism and cognitive impairment in Alzheimer’s disease

Abstract: Alzheimer’s disease (AD) is characterized by amyloid deposition, brain hypometabolism, gray matter atrophy and cognitive decline, yet their causal interactions are…

Date: 2026-09-15