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A systems-level analysis of global gene expression in resistant and susceptible Biomphalaria glabrata in response to Schistosoma mansoni infection

Abstract: The freshwater gastropod Biomphalaria glabrata is the major intermediate host of Schistosoma mansoni , the causative agent of human schistosomiasis. Elucidating the…

Date: 2026-09-15

Immunosuppression as an associated risk factor for high-grade cervical lesions: a comparative study of cytology, HPV, and histopathology

Abstract: Persistent high-risk human papillomavirus (hrHPV) infection is the main cause of cervical carcinogenesis, and impaired immune surveillance may increase the risk of viral…

Date: 2026-09-15

Impact of molecular profiling in patients with endometrial cancer: real world experience from India

Abstract: The introduction of The Cancer Genome Atlas (TCGA) had made a paradigm shift towards molecular based classification that impacted the treatment of endometrial cancer…

Date: 2026-09-15

Efficacy and safety analysis of induction therapy for unresectable locally advanced non-small-cell lung cancer: a retrospective study based on IPTW

Abstract: Concurrent chemoradiotherapy (cCRT) followed by consolidation immunotherapy constitutes the current standard of care for unresectable locally advanced non–small cell…

Date: 2026-09-15

Transcriptomics, identification, and testing of manganese metabolism-related genes in cervical squamous cell carcinoma

Abstract: Cervical squamous cell carcinoma (CSCC) remains a leading cause of cancer-related mortality in women, and few effective prognostic biomarkers have been identified.…

Date: 2026-09-15

Integration of MRI radiomics with immune profiling to predict response to CDK6 inhibitors in high-grade glioma

Abstract: Predictive biomarkers are needed to identify patients with high-grade glioma who benefit from cyclin-dependent kinase 6 (CDK6) inhibition. We hypothesized that an…

Date: 2026-09-15

Impact of ALC Nadir and EDRIC on survival outcomes in limited-stage small cell lung cancer receiving chemoradiotherapy: a retrospective analysis comparing twice-daily and once-daily radiotherapy

Abstract: This study aimed to evaluate the prognostic value of absolute lymphocyte count (ALC) nadir and estimated dose of radiation to immune cells (EDRIC) in patients with…

Date: 2026-09-15

Impaired antigen clearance of macrophages associates with heart failure and non-obstructive azoospermia: insights from transcriptomics, in silico knockout, and in vitro validation

Abstract: Heart failure (HF) and non-obstructive azoospermia (NOA) are high-burden diseases that share chronic inflammation and tissue injury. Macrophages are key regulators in…

Date: 2026-09-15

Prognostic value of soluble ST2 in cardiac magnetic resonance defined myocardial infarction with non-obstructive coronary arteries

Abstract: Cardiac magnetic resonance (CMR) plays an essential role in identifying the underlying etiology of myocardial infarction with non-obstructive coronary arteries (MINOCA).…

Date: 2026-09-15

Latent profiles and transitions of acute psychological stress in patients with acute myocardial infarction after percutaneous coronary intervention and their association with cardiac rehabilitation participation

Abstract: To explore the dynamic transitions of latent profiles of acute psychological stress in patients with acute myocardial infarction across three time points and their…

Date: 2026-09-15