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A Zap70 gain-of-function mutation alters mouse thymic maturation

Abstract: The tyrosine kinase ZAP-70 is essential for T-cell activation and development, but the mechanisms regulating its activity remain unclear. Previous studies showed that…

Date: 2026-10-06

Macro-micro dynamics of child undernutrition in Pakistan: a structural learning-based Bayesian network analysis of household and policy drivers

Abstract: Child undernutrition remains a major public health concern and creates health-related inequalities in developing countries, with long-term consequences for human…

Date: 2026-10-06

Rethinking networks through relatedness - a qualitative study among inpatients in forensic psychiatry

Abstract: Recovery-oriented approaches in forensic psychiatry increasingly emphasize the importance of social relationships. However, research and practice have primarily…

Date: 2026-10-06

Lion Hearts: applying implementation mapping to plan the delivery of a family-based physical activity intervention in community CrossFit affiliates

Abstract: Community-based physical activity interventions face challenges in adoption, implementation, and sustainability. Lion Hearts is a family-based physical activity…

Date: 2026-10-06

Clinical factors predicting tic persistence into adulthood

Abstract: Despite widespread patient and family interest in long-term outcome prediction at the time of Tourette syndrome (TS) diagnosis, there is limited data on factors…

Date: 2026-10-06

Expression of estrogen receptor and progesterone receptor in endometrial cancer and their correlations with clinicopathological features

Abstract: To investigate the expression levels of estrogen receptor (ER) and progesterone receptor (PR) in endometrial carcinoma (EC) and their correlations with standardized…

Date: 2026-10-06

Effectiveness of a multicomponent PDCA-based infusion safety management strategy in patients with pulmonary tuberculosis: a non-randomized historical-control study

Abstract: To evaluate the association between a multicomponent PDCA-based infusion safety management strategy and intraoperative peripheral intravenous (PIV) outcomes in adults…

Date: 2026-10-06

Macrophage BMPRIB mediates p38-dependent inflammatory reprogramming and chemotaxis during ventilator-induced lung injury

Abstract: Ventilator-induced lung injury (VILI) is a major iatrogenic complication of mechanical ventilation, in which dysregulated inflammation, particularly macrophage-driven…

Date: 2026-10-06

Association between affective temperaments and thalamic nuclei volumes

Abstract: Affective temperaments are stable, biologically based traits that may represent subclinical manifestations or premorbid phenotypes of mood disorders. The thalamus is…

Date: 2026-10-06

Adverse childhood experiences and functional stability in the affective-to-psychotic spectrum: a longitudinal multistate analysis of employment and relationship outcomes

Abstract: Adverse childhood experiences (ACEs) exert transdiagnostic influences on disorders of the affective-to-psychotic spectrum which share genetic similarities. While ACEs…

Date: 2026-10-06