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Clinical, immunological, and radiological characteristics of pulmonary involvement in childhood-onset primary Sjögren’s syndrome: a single-center retrospective study

Abstract: To describe pulmonary involvement in childhood-onset primary Sjögren’s syndrome (cSS). This retrospective study included 17 children with cSS diagnosed at Jiangxi…

Date: 2026-10-06

Complement and immunoglobulin profiles in ANCA-associated vasculitis with renal involvement: a serotype-stratified analysis of disease activity and renal outcomes

Abstract: ANCA-associated vasculitis (AAV) is characterized by pauci-immune small-vessel inflammation driven predominantly by neutrophil activation, in contrast to…

Date: 2026-10-06

Integrated immunoreactivity analysis of MHC-I epitopes derived from the Marburg virus glycoprotein

Abstract: Marburg virus (MARV) is a hemorrhagic fever virus, and its glycoprotein (GP) represents an important target for vaccine research. MHC class I (MHC-I)-restricted T cell…

Date: 2026-10-06

Widening educational inequalities in type 2 diabetes risk and mediators across successive generations: a prospective cohort study

Abstract: Lower educational attainment has been associated with incident T2DM and adverse outcomes among people with established diabetes, but these stages have largely been…

Date: 2026-10-06

Comparative prognostic analysis of allogeneic hematopoietic stem cell transplantation regimens in the treatment of severe aplastic anemia

Abstract: Severe aplastic anemia (SAA) is a fatal bone marrow failure disorder. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the definitive curative treatment…

Date: 2026-10-05

Investigating risk factors and developing a predictive model for venous thromboembolism in patients with sepsis

Abstract: Patients with sepsis are at high risk for venous thromboembolism (VTE). However, existing assessment tools designed for general medical or surgical populations may…

Date: 2026-10-05

Long-term clinical outcomes in females with precocious puberty treated with gonadotropin-releasing hormone analogues

Abstract: To evaluate long-term anthropometric, metabolic, reproductive, and bone mineral density (BMD) outcomes in girls with central precocious puberty (CPP) treated with…

Date: 2026-10-05

Cardiovascular risk factors in autoimmune thyroiditis: role of adiponectin, resistin, inflammation and auto-immunity - a cross-sectional study

Abstract: Autoimmune thyroiditis (AIT) has been associated with an increased cardiovascular risk. Whether adipokines, inflammation and auto-immunity contribute to this increased…

Date: 2026-10-05

Machine learning-derived R-loop-related diagnostic signature for psoriasis: a multi-cohort and single-cell validation study

Abstract: Psoriasis is a chronic inflammatory skin disease characterized by dysregulated immune responses and keratinocyte (KC) hyperproliferation. Although therapeutic strategies…

Date: 2026-10-05

FeNO may serve as a noninvasive screening tool for gastroesophageal reflux disease in children under 5 years: a retrospective study

Abstract: To investigate the correlation between fractional exhaled nitric oxide (FeNO) measurement and pediatric gastroesophageal reflux disease (GERD), explore potential…

Date: 2026-10-05