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Inpatient continuous glucose monitoring halves the risk of hypoglycemia in patients with hyperinsulinism

Abstract: Patients with congenital hyperinsulinism (HI) face recurrent and unpredictable hypoglycemia. Conventional inpatient monitoring relies on intermittent fingerprick glucose…

Date: 2026-10-15

Gut bacterial lauroyl tryptamine reduces GPR183-associated inflammatory responses in human macrophages and T cells in vitro

Abstract: Recent research has highlighted the role of gut microbiota in producing bioactive metabolites that interact with G-protein coupled receptors (GPRs) and influence immune…

Date: 2026-10-15

A multicohort proteomics-based machine learning score (MASHPredict) for noninvasive diagnosis and long-term prognostication of metabolic dysfunction-associated steatohepatitis

Abstract: Metabolic dysfunction-associated steatohepatitis (MASH) can progress to cirrhosis and hepatocellular carcinoma, yet the invasiveness of liver biopsy limits its clinical…

Date: 2026-10-15

Clinical manifestations of resistance to thyroid hormone beta (RTH?) syndrome in children – multicenter case series

Abstract: Resistance to thyroid hormone (TH) ? (RTH?) is a rare genetic disorder caused by mutations in the TH receptor ? gene ( THRB ) and characterized by elevated TH levels…

Date: 2026-10-15

Quality of life before and after sympathectomy in primary hyperhidrosis: a recall-based paired analysis of 94 patients

Abstract: Primary hyperhidrosis substantially impairs quality of life. Sympathectomy is an established treatment for severe focal hyperhidrosis; however, patient-reported outcomes…

Date: 2026-10-15

Normative functional network localization of gray matter alterations in idiopathic generalized epilepsy

Abstract: Idiopathic generalized epilepsy (IGE) has traditionally been considered a non-lesional epilepsy syndrome on conventional MRI, yet voxel-based morphometry (VBM) studies…

Date: 2026-10-15

Effects of combined GnRHa and letrozole on serum steroid profiles in girls with advanced bone age

Abstract: To evaluate the impact of combined GnRHa and letrozole on serum steroid profiles (classical, 11?oxygenated, and backdoor androgen pathways) in girls with advanced bone…

Date: 2026-10-15

Nutritional literacy profiles and their association with dietary motivation in adolescents with chronic kidney disease

Abstract: To explore potential categories of nutritional literacy among adolescents with chronic kidney disease and differences in dietary motivations across these categories.…

Date: 2026-10-15

Epidemiology and outcomes in pediatric neuroblastoma: a US population-based study

Abstract: Neuroblastoma is a heterogeneous pediatric malignancy with variable outcomes. This study aimed to evaluate survival outcomes and identify independent prognostic factors…

Date: 2026-10-15

Computed tomography multi-phase radiomics models for differentiating benign and malignant thyroid nodules

Abstract: To develop and validate an integrated model combining multiphase CT radiomics features, clinical data, and conventional morphological CT signs for the preoperative…

Date: 2026-10-15