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Long-term visual outcomes and rotational stability of two diffractive toric intraocular lenses with different design combinations in cataract patients with long axial length

Abstract: Selecting intraocular lenses (IOLs) for cataract patients with long axial length remains challenging. Two diffractive toric IOLs with distinct design…

Date: 2026-10-01

Underwater hybrid ESD versus conventional ESD for colorectal laterally spreading tumors: a retrospective study

Abstract: Conventional endoscopic submucosal dissection (C-ESD) is standard for colorectal laterally spreading tumors (LSTs) but is time-consuming. Underwater hybrid ESD (U-Hybrid…

Date: 2026-10-01

Early high-dose intravenous methylprednisolone is associated with faster symptom improvement in persistent ocular myasthenia gravis: a single-center retrospective study

Abstract: High-dose intravenous methylprednisolone pulse therapy (HMP) may provide rapid symptom relief in ocular myasthenia gravis (MG), but the clinical impact of its early use…

Date: 2026-10-01

Identification of Akkermansia muciniphila as a candidate gut commensal involved in the pathogenesis of rheumatoid arthritis

Abstract: The “mucosal origins hypothesis” posits that mucosal sites, such as the gut, are initial sites where immune responses first develop that may, months to years later,…

Date: 2026-10-01

Anti?PD?1/CTLA?4 bispecific antibody?based combination therapy for cervical cancer: a multicenter study with biomarker analysis

Abstract: Cadonilimab is a PD?1/CTLA?4 bispecific antibody with robust activity in platinum?pretreated advanced cervical cancer, while its first?line value and resistance…

Date: 2026-10-01

Peptide optimization to improve antigen presentation and antitumor responses in sarcoma

Abstract: Sarcomas are rare and heterogeneous malignancies for which therapeutic options remain limited, particularly in advanced disease. Standard treatments, including surgery,…

Date: 2026-10-01

Systemic immune activation coexists with compartment-specific regulatory enrichment in matched blood, peritumor, and tumor tissue from advanced oral squamous cell carcinoma

Abstract: Oral squamous cell carcinoma (OSCC) is the most prevalent form of oral cancer and is characterized by a poor prognosis and frequent immune evasion. While the tumor…

Date: 2026-10-01

Screening of risk factors and construction of a prediction model for enteral nutrition intolerance in elderly patients with comorbidities and sarcopenia

Abstract: To screen the independent risk factors for enteral nutrition intolerance (ENI) in elderly comorbid patients with sarcopenia, and to establish and validate a clinical…

Date: 2026-10-01

Identification of a novel inflammatory mast cell subpopulation in triple-negative breast cancer

Abstract: Triple-negative breast cancer (TNBC) is associated with poor therapeutic outcomes, and increasing attention has been directed toward the tumor microenvironment (TME).…

Date: 2026-10-01

Disproportionality analysis of adverse event reporting with aspirin, statins, and their co-exposure in FAERS, 2004–2025

Abstract: To characterize and compare adverse-event reporting patterns for aspirin without statins, statins without aspirin, and aspirin–statin co-exposure in the FDA Adverse…

Date: 2026-10-01