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Isoimperatorin alleviates fungal keratitis by regulating NF-?B pathway and macrophage immune response

Abstract: The purpose of this research study was to investigate the impact of isoimperatorin on Aspergillus fumigatus (A. fumigatus) keratitis and elucidate its underlying…

Date: 2026-01-27

The influence of social support on active aging in chronic disease patients among older adults: mediating role of coping strategies

Abstract: Active aging is pivotal for addressing population aging. Older adults chronic disease patients face greater active aging challenges, and while social support and coping…

Date: 2026-01-27

Clinical application of the femoral neck system in the treatment of femoral neck fractures

Abstract: The research was conducted to assess the therapeutic efficacy of the femoral neck system (FNS) and cannulated compression screw (CCS) in treating femoral neck fractures…

Date: 2026-01-27

Identification of key genes associated with muscle atrophy after spinal cord injury and experimental verification in rats

Abstract: Spinal cord injury (SCI) is a neurological disease with high morbidity and mortality. Post-SCI muscle atrophy is a cascade response to SCI, and failure to actively…

Date: 2026-01-27

The association between social determinants, lifestyle and metabolic factors and the onset of secondary glenohumeral joint osteoarthritis: a cohort study of adults in the UK

Abstract: Secondary Glenohumeral Joint Osteoarthritis (GJO) is a degenerative condition of non-weight-bearing joints. While age and gender are known risk factors, the role of…

Date: 2026-01-27

Development and evaluation of a machine learning model to predict unplanned readmission risk in patients with ulcerative colitis

Abstract: Ulcerative colitis (UC), a chronic inflammatory bowel disease marked by recurrent flares and remissions, often necessitates repeated hospitalization owing to disease…

Date: 2026-01-27

The predictive potential of surrogate indicators of insulin resistance for type 2 diabetic kidney disease

Abstract: Approximately 40% of patients with diabetes develop diabetic kidney disease (DKD), necessitating renal replacement therapy such as dialysis or transplantation.…

Date: 2026-01-27

Association between early depressive symptoms after stroke and trajectories of functional recovery among patients with acute ischemic stroke: a longitudinal study

Abstract: Depressive symptoms are very common in the acute phase of stroke; however, its impact on distinct functional recovery trajectories in acute ischemic stroke (AIS)…

Date: 2026-01-27

A GPT-reinforced social robot for patient communication: a pilot study

Abstract: Quality healthcare requires effective patient communication. However, lack of personnel and increasing demands on healthcare professionals (HCPs) create a need for…

Date: 2026-01-27

Development and computational analysis of high dimensional spectral flow cytometry data for the resolution of innate lymphoid cells in the mammary tumor microenvironment

Abstract: Spectral flow cytometry has ushered in a new era in immunology. Through the improvement of the resolution of surface and intracellular protein expression, this approach…

Date: 2026-01-27