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Association between the platelet-albumin-bilirubin score and all-cause mortality in ICU-admitted heart failure patients: a retrospective cohort analysis and machine learning-based prognostic modeling

Abstract: The platelet-albumin-bilirubin (PALBI) score has shown prognostic value across multiple medical conditions; nevertheless, its effectiveness in forecasting prognoses…

Date: 2025-10-23

Identification and validation of plasma protein biomarkers as therapeutic targets in acute myeloid leukemia: an integrative multi-omics study

Abstract: Acute myeloid leukemia (AML) remains a therapeutic challenge due to its high relapse rate and limited treatment options. This study aimed to identify and validate novel…

Date: 2025-10-22

Endolysin significantly improves symptoms with atopic dermatitis: bridging the gap from research to clinical practice

Abstract: Atopic Dermatitis (AD), a chronic inflammatory skin disease characterized by pruritus, dryness, redness, edema, scratching, and lichenification, ranks as the leading…

Date: 2025-10-22

The clinical application of ear keloid using five-blade core excision combined with pressure and superficial electron beam radiation

Abstract: Surgical removal is the primary method for the clinical treatment of ear keloids. However, there are numerous surgical options available, and no standardized approach in…

Date: 2025-10-22

Maternal obesity phenotype, metabolic dysfunction, and preterm birth: a prospective birth cohort study

Abstract: The purpose of this research was to examine the relationship between metabolic obesity phenotypes and preterm birth (PTB) as well as the impact of obesity and metabolic…

Date: 2025-10-22

RAD51 protein is a predictor of chemosensitivity and survival prognosis in patients with advanced high-grade serous ovarian cancer undergoing neoadjuvant chemotherapy

Abstract: The primary aim of this study is to investigate the relationship between the expression of the homologous recombination protein RAD51 and the CA125 elimination rate…

Date: 2025-10-22

Perceptions and satisfaction among couples on male involvement during pregnancy: a cross-sectional study

Abstract: Previous studies showed that male involvement during pregnancy could improve maternal and newborn outcomes. However, little is known about the perceptions and…

Date: 2025-10-22

Healthcare needs and barriers to care among female partners of male suspects of child sexual abuse material offences in Sweden: a qualitative interview study

Abstract: To explore the impact on female partners of the discovery that their significant other is under investigation for Child Sexual Abuse Material (CSAM) offences, with a…

Date: 2025-10-22

Factors influencing medical students in a lower-middle income country to consider psychiatry as a career option

Abstract: To assess and identify the environmental, curriculum, teaching related factors and preconception about psychiatry that influence medical students’ attitudes toward…

Date: 2025-10-22

Prevalence, associated factors, and perceived causes of mental distress among visitors to holy water in Mekelle town, Tigray, North Ethiopia

Abstract: In low-income countries, mental disorders contribute to 12% of the global burden of disease compared to 8.1% in developed countries. Seeking help from religious…

Date: 2025-10-22